Using of several simulation software we are able to calculate and visualise forces, stresses and strains of loaded structures. Thus, we achieve informations about internal wear of tissues beyond in vitro and in vivo experiments. With parameter studies we furthermore have the opportunity to investigate the influence of single parameters on global result parameters.
There are many development steps to go until a simulation or a finite element model is valid enough to give continuative predictions.

From bone to model: Based on a multitude of computer tomographies, x-rays or MRT images of an anatomical structure digital datasets are generated. The outcome of these is a volume model and finally a finite element grid.
The single finite elements are equipped with mechanical and viscoelastic properties and material parameters that are known from experiments and literature. Finally the whole model is validated with an in-vitro experiment. This means that the model behaviour is compared with the mechanical reality.
Only now the model can be used for further predictions like in-vivo and in-vitro not measurable forces and deformations, breakdown forecast of an anatomical structure or the estimated behaviour of implants within this anatomical structure.
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Resulting strains in an intervertebral disc implant
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Finite element analysis of the knee joint (bone, cartilage, menisci)
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Computer model of the human lower extremity musculature